陈绍恢,男,汉族,湖北咸宁人,1989年7月出生,讲师,硕士生导师。主要从事胚胎干细胞多能性维持机制以及lncRNA在核高级结构中的作用方面研究。近年来,主持省部级项目一项、校级项目两项,发表SCI论文多篇。
一、科研项目
1、湖北省自然科学基金面上项目,lnc1700007L15Rik在小鼠胚胎干细胞多能性维持的功能和机制,2022/06-2024/06,8万元,主持。
2、湖北科技学院博士启动基金项目(BK20221),邻苯二甲酸酯对小鼠社交缺陷的影响及其机制研究,,2021/09-2024/09,15万元,主持。
3、经口暴露邻苯二甲酸酯对小鼠社交缺陷的影响及其机制研究,2021年度医学部口腔与眼视光医学院专项科研基金项目重点项目(2021WG06),2022 /01-2025/01,5万元,主持。
二、科研论文
代表性论文
1. Shaohui Chen, Bohan Chen, Shaohui Chen, Bohan Chen, Guangsong Su, Jun Chen, Dianhao Guo, Qingqing Yin, Wenbin Wang, Zhongfang Zhao, Lei Zhang*, Jiandang Shi*, Wange Lu*. Branched-chain amino acid aminotransferase-1 regulates self-renewal and pluripotency of mouse embryonic stem cells through Ras signaling. Stem cell Research, 2020, 49, 102097. DOI: 10.1016/j.scr.2020.102097
2. Shaohui Chen#, Huihui You#, Lin Mao, Xu Yang*. Dibutyl phthalate induced oxidative stress does not lead to a significant adjuvant effect on a mouse asthma model. Toxicology Research, 2015, 4(2), 260-269. DOI: 10.1039/c4tx00096j
其他论文
1. Huihui You, Shaohui Chen, Lin Mao, Bin Li, Ye Yuan, Rui Li*, Xu Yang*. The adjuvant effect induced by di-(2-ethylhexyl) phthalate (DEHP) is mediated through oxidative stress in a mouse model of asthma. Food and Chemical Toxicology, 2014, 71: 272–281. DOI: 10.1016/j.fct.2014.06.012
2. Huihui You, Rui Li, Chenxi Wei, Shaohui Chen, Lin Mao, Zhenye Zhang*, Xu Yang*. Thymic Stromal Lymphopoietin Neutralization Inhibits the Immune Adjuvant Effect of Di-(2-Ethylhexyl) Phthalate in Balb-c Mouse Asthma Model. PLoS One, 2016, 11(7): e0159479. DOI: 10.1371/journal.pone.0159479
3. Biao Yan, Ping Ma, Shaohui Chen, Hongguo Cheng, Min Tang, Yanling Sun, Xu Yang, Yang Wu, Menglin Cheng*. Nimodipine attenuates dibutyl phthalate induced learning and memory impairment in kun ming mice: An in vivo study based on bioinformatics analysis. Environmental Toxicology; 2020, 1–10. DOI: 10.1002/tox.23084
4. Peng Song, Biao Yan, Fan Lei, Zhuonan Qiu, Chi Zhang, Yang Wu, Shaohui Chen, Xu Yang, Dingwen Shen*, Ping Ma*. Continuous artificial light at night exacerbates diisononyl phthalate-induced learning and memory impairment in mice: Toxicological evidence. Food and Chemical Toxicology, 2021, 151: 112102. DOI: 10.1016/j.fct.2021.112102